1522
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| Years: 1519 1520 1521 - 1522 - 1523 1524 1525 | |
| Decades: 1490s 1500s 1510s - 1520s - 1530s 1540s 1550s | |
| Centuries: 15th century - 16th century - 17th century | |
Events
- January 9 - Adrian Dedens becomes Pope Adrian VI.
- February 26 - Execution by hanging of Cuauhtémoc, Aztec ruler of Tenochtitlan under orders of conquistador Hernán Cortés.
- April 22 - Battle of Bicocca - French and Swiss forces under Odet de Lautrec are defeated by the Spanish in their attempt to retake Milan, and are forced to withdraw into Venetian territory.
- July 28 - Beginning of Ottoman Sultan Suleiman I's siege of the Knights of St. John in Rhodes.
- September 6 - The Vittoria, one of the surviving ships of Ferdinand Magellan's expedition, returns to Sanlcar de Barrameda in Spain, becoming the first ship to circumnavigate the world.
- December 18 - The Turks finally break into Rhodes, but the Knights continue fierce resistance in the streets.
- December 20 - Suleiman the Magnificent accepts the surrender of the surviving Knights, who are allowed to evacuate. They eventually re-settle on Malta and become known as the Knights of Malta.
- First Diet of Nuremberg.
- The third edition of the Textus Receptus of the Bible published.
Births
- March 28 - Albert the Warlike, German prince (died 1557)
- Catharine de Ricci, Italian prioress (died 1590)
- Emperor Gelawdewos of Ethiopia (died 1559)
- Adriana of Antwerp, wife of John Rogers
- May 24 - John Jewel, bishop of Salisbury (died 1571)
- Lamoraal Egmond, Flemish general and political figure (died 1568)
- November 18 - Lamoral, Count of Egmont, Flemish general and statesman (died 1568)
- February 2 - Lodovico Ferrari, Italian mathematician (died 1565)
- Sen no Rikyu, codifer of the Japanese tea ceremony (died 1591)
- September 11 - Ulissi Aldrovandi, Italian naturalist (died 1605)
- November 9 - Martin Chemnitz, Lutheran reformer (died 1586)
Deaths
- February 25 - William Lilye, English scholar (born 1468)
- April - Eleni, Queen of Ethiopia
- June 25 - Franchinus Gaffurius, Italian music theorist and composer (born 1451)
- October 30 - Jean Mouton, French composer (born 1459)
- Gavin Douglas, Scottish poet and bishop
- Fiorenzo di Lorenzo, Italian painter (born 1440)
- Johann Reuchlin, German humanist and Hebrew scholar
- Henry Stafford, 1st Earl of Wiltshire, English nobleman (born 1479)af:1522
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