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Structural genomics

From Academic Kids

Structural genomics or structural bioinformatics refers to the analysis of macromolecular structure particularly proteins, using computational tools and theoretical frameworks. One of the goals of structural genomics is the extension of idea of genomics, to obtain accurate three-dimensional structural models for all known protein families, protein domains or protein folds. Structural alignment is a tool of structural genomics.

See also

Databases

References

Books

Hallmark publications

  • Richardson, J.S. (1981) "The anatomy and taxonomy of protein structure". Adv. Protein Chem., 34, 167-339.
  • G.N. Ramachandran, C. Ramakrishnan, and V. Sasisekharan. "Stereochemistry of polypeptide chain configurations". J. Mol. Biol., 7:95-9, 1963.
  • G.N. Ramachandran and V. Sasisekharan. "Conformation of polypeptides and proteins". Adv. Protein Chem., 23:283-438, 1968.

External links

Research centers

Software

  • PyMOL viewer (http://www.pymol.org/)
  • VMD viewer (http://www.ks.uiuc.edu/Research/vmd/)
  • MolMol viewer (http://www.mol.biol.ethz.ch/wuthrich/software/molmol/)
  • SPDBV DeepView viewer (http://www.expasy.org/spdbv/)
  • STRIDE (http://www.embl-heidelberg.de/argos/stride/stride_info.html)
  • PROCHECK (http://www.biochem.ucl.ac.uk/~roman/procheck/procheck.html) a web service
  • iMolTalk (http://i.moltalk.org) a webservice
  • Jmol (http://www.jmol.org/) - molecular viewer Java applet with rasmol-like scripting capabilities and javascript interaction

Template:Biosci-stub


Genomics topics
Genome project | Glycomics | Human Genome Project | Proteomics | Structural genomics
Bioinformatics | Systems biology
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