Globus pallidus
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The external segment of the globus pallidus
The external segment of the globus pallidus consists mostly of neurons that send axons to the subthalamic nucleus, substantia nigra pars reticulata, and the internal segment of the globus pallidus, where they release the neurotransmitter GABA. It receives GABAergic inputs from the striatum and also a reciprocal glutamatergic projection from the subthalamic nucleus. It is sometimes used as a target for deep brain stimulation as a treatment for Parkinson's disease.
The internal segment of the globus pallidus
The internal segment of the globus pallidus is one of the output nuclei of the basal ganglia (the other being the substantia nigra pars reticulata). The GABA-containing neurons send their axons to various thalamic and brain stem nuclei.
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