Gamma glutamyl transpeptidase
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Gamma glutamyl transferase (GGT or GGTP, or Gamma-GT) (EC 2.3.2.2 (http://us.expasy.org/cgi-bin/nicezyme.pl?2.3.2.2)) is a liver enzyme. Its level in the blood may be tested for, as an elevated level may indicate an abnormality in the liver, though this can be caused by a number of conditions including:
- congestive heart failure
- cholestasis (congestion of the bile ducts)
- cirrhosis of the liver
- Restricted blood flow to the liver
- Necrosis of the liver
- Liver tumors
- hepatitis
- hepatotoxic drugs
Its levels are increased in chronic and acute alcohol abuse.
References
- Medline Plus (http://www.nlm.nih.gov/medlineplus/ency/article/003458.htm)