5-MeO-DMT
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5-MeO-DMT | |
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Chemical formula | C13H18N2O |
Chemical name | 5-Methoxy-N,N-dimethyltryptamine or 5-methoxy-3-[2-(dimethylamino)ethyl]indole |
Molecular mass | 218.298 g/mol |
Melting point | 67.7 °C (154 °F) |
CAS number | 1019-45-0 |
SMILES | COC1=CC2=C(NC=C2CCN(C)C)C=C1 |
5-MeO-DMT is one of the most potent psychedelic entheogens known to man. It is found in a wide variety of plant species and has been used by South American shamans for over 1200 years.
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Chemistry
5-MeO-DMT was first synthesized in 1936, and in 1959 it was isolated as one of the psychoactive ingredients of Anadenanthera peregrina seeds used in cohoba snuff.
History
Traditionally 5-MeO-DMT was used as a psychedelic snuff or as a constituent of preparations of Ayahuasca. It is also the major ingredient of the venom of Colorado River toad (Bufo alvarius), although there is no direct evidence this was used as an entheogen until recent times.
Use
When used as a drug in its purified form, 5-MeO-DMT is smoked, snorted, or injected and is active at a dose of as little as 2mg. The onset of effects occurs in seconds after smoking/injecting, or minutes after insufflating, and the experience is often described as similar to a Near Death Experience. It can also become orally active with the use of an monoamine oxidase inhibitor to inhibit its quick metabolism.
5-MeO-DMT can also be obtained from psychoactive toads like the Colorado River toad.
External links
- TiHKAL #38 on Erowid (http://www.erowid.org/library/books_online/tihkal/tihkal38.shtml)
- Erowid's 5-MeO-DMT Vault (http://www.erowid.org/chemicals/5meo_dmt/5meo_dmt.shtml)
Psychedelic tryptamines edit (https://academickids.com:443/encyclopedia/index.php?title=Template:Hallucinogenic_tryptamines&action=edit) |
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5-MeO-AMT 5-MeO-DIPT 5-MeO-DMT AMT Bufotenin DET DIPT DMT DPT Ethocin Iprocin Psilocin Psilocybin |