Talk:Human Genome Project
|
|
Decent article, but it doesn't explain how the genome was sequenced. Can anyone in the know write a section explaining the techniques used to sequence the entire thing, including shotgun sequencing? I have a vague idea, but not enough to write an entire section on it.
Very good article. One thing though: you might want to include something about some of the criticism of the HGP, particularly concerns about whether the benefits will be worth the cost and the "genomania" surrounding
didn't the HGP only sequence euchromatic DNA, skipping the heterochromatic DNA? So that it would be more correct to say "The Human Genome Project (HGP) endeavoured to map the euchromatic human genome down to the nucleotide (or base pair) level and to identify all the 30-35,000 genes present in it."? -- Nunh-huh 01:34, 20 Feb 2004 (UTC)
Is this relevant to the article?
http://www.jgi.doe.gov/News/news_9_15_04.html
This DOE link reports the "final sequence analysis" of chromosome 5 on September 15th, 2004. They mention that it is the 12th chromosome to be polished with another 12 to go. Should we mention this?
The October Scientific American has a fascinating article about the so called "junk" DNA that makes up most of the human genome. According to the article, this non-protein coding DNA may well code for RNA sequences the cell uses to control cellular processes. Proteins make up the "bricks and morter" of the cell, but the non-protein coding portions may represent the blueprint on how the build the organism. If so, we are only just beginning to understand the full scope of DNA's role in inheritance.
dates?
The dates are mostly wrong, right?
- could you be more specific? Courtland 00:34, 2005 Feb 18 (UTC)
- how can it have started in 1990, expected to have taken 15 years, finished in 2000 and be only two years early?