Tupac (disambiguation)
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- Tupac Inca Yupanqui, Inca
- Túpac Amaru, the last Sapa Inca (16th century)
- Túpac Amaru II, a 18th century rebel leader and matrilineal descendant of the Supa Inca Tupac Amaru
- Tupac Shakur, a 20th century Los Angeles rapper