RSI
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RSI may refer to:
- Rapid sequence induction, a form of anesthesia
- Relative strength index, a security market indicator measuring the relative gains, over relative losses, over time
- Repetitive strain injury, a disorder affecting bone and muscle from repetitive movements such as typing
- Repubblica Sociale Italiana or Italian Social Republic
- Research Science Institute, a summer research program held at MIT for high school juniors
- Revenue and Social Insurance numbers in the Republic of Ireland
- Residual self image, the self-projected image of oneself inside the Matrix; your character on the game The Matrix Online