Ohio State Highway 21

Ohio State Highway 21 is a relic of an old U.S. Highway 21, a major north-south highway that connected greater Cleveland, Ohio to southern South Carolina. South of Strasburg, Ohio, near the current southern terminus of Ohio 21, the designation of U.S. 21 was moved to the new Interstate 77 freeway in east-central and southeastern Ohio by the early 1970s and then decommissioned. North of Strasburg, what remained of U.S. 21 as a route separate of Interstate 77 became Ohio 21.

Ohio 21 survives in greater Cleveland as a divided surface road between its current northern terminus at Interstate 77 and Interstate 480 and Interstate 77 just south of the Ohio Turnpike, serving some of the suburbs of Cleveland as a local through route. It coincides with Interstate 77 between two junctions at mileposts 146 and 135 (from north to south) and again splits, Ohio 21 passing through Barberton, Ohio and Massillon, Ohio, Interstate 77 passing through the much largger cities of Akron, Ohio and Canton, Ohio. Ohio 21 has its southern terminus south of Strasburg at milepost 87.

Very heavily traveled before the Interstate era, much of Ohio 21 is divided highway or even freeway due to the needs of the time.

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