Academia
Business
- Rocky Aoki, restaurateur (the Benihana chain) and his wife
- Edgar Bronfman, Jr., Seagram Company CEO, and his former wife Sherry Brewer Bronfman, actress
- Andrea Jung, Avon products, and husband Michael Gould
- Robert Kiyosaki, Rich Dad Company, and wife Kim
- Russell Simmons, record producer, and wife Kimora Lee Simmons, model
Entertainment
- Woody Allen and wife Soon-Yi Previn
- Rowan Atkinson, comedian, and his wife, Sunetra Sastry
- Bai Ling, actress, and partner Chris Isaak
- Josephine Baker dancer, and her husband
- Harry Belafonte, singer and his wife Julie
- David Bowie and wife Iman
- Nicolas Cage and wife Alice Kim
- Michael Caine, actor, and his wife Shakira (née Shakira Baksh)
- Diahann Carroll, actress and former husband Vic Damone, singer
- Dave Chappelle, comedian, and his wife
- Rosalind Chao, actress, and husband Simon Templeman
- Maggie Cheung, actress and (1) ex-husband Olivier Assayas (married 1998-2001) and (2) partner Guillaume Brochard
- Tommy Chong, comedian, and former wife Maxine Sneed (married 1960-1970)
- Christy Chung, actress, and ex-husband Glen Ross
- Tyne Daly and husband George Sanford Brown
- Sammy Davis, Jr. and wife May Britt (1960-1968)
- Robert De Niro, actor, and his former wife
- Taye Diggs and wife Idina Menzel
- Katherine Dunham, dancer and her husband, John Pratt, producer
- Dawn French, comedienne and husband Lenny Henry, comedian
- Whoopi Goldberg and (1) Ted Danson actor, (2) partner Frank Langella, actor
- Cuba Gooding, Jr, and wife Sara Kapfer
- Lena Horne and husband Lennie Hayton
- C. Thomas Howell, actor, and his former wife, Rae Dawn Chong, actress (married 1989-1990)
- Julio Iglesias, singer and his former wife Isabel Preysler (divorced 1985)
- Quincy Jones and wife Peggy Lipton
- John Lennon and wife Yoko Ono (married 1969-1980)
- Lucy Liu, actress, and fiancé Zack Helm
- Jennifer Lopez, singer and (1) former partner Puff Daddy rap artist, (2) former fiance Ben Affleck, actor
- Yo-yo Ma, cellist, and his wife Jill Hornor, violinist
- Thandie Newton, actress and husband Oliver Parker, director
- Sandra Oh, actress, and husband Alexander Payne, director
- Linda Park, actress, and partner Tom Hardy
- Sidney Poitier and his wife Joanna Shimkus
- Diana Ross and ex-husband Robert Silberstein (1971-1976), Arne Naess
- Roxie Roker, actress and husband Sy Kravitz, producer
- Mort Sahl, comedian, and first wife China Lee, Playboy playmate
- Seal, singer, and his wife, Heidi Klum, model
- John Simmons, bassist and his wife
- Wesley Snipes and wife Nikki Park
- Mathieu Kassovitz and wife Julie Mauduech
- Tina Turner and partner Erwin Bach
Politics
- Kofi Annan, UN Secretary General, and wife Nane Annan
- Carol Moseley Braun, former United States Senator and Ambassador to New Zealand, and her husband, Michael Braun (married from 1973 to 1986)
- John Ellis (‘Jeb’) Bush, Florida Governor, and his wife, Columba
- Bob Carr, Australian New South Wales Premier and his wife, Helena
- Elaine Chao, US Secretary of Labor, and husband Mitch McConnell, Kentucky senator
- Adrienne Clarkson, Canadian Governor General, and husband John Ralston Saul
- Frederick Douglass, American abolitionist and his wife, Helen Pitts
- Joschka Fischer, German Minister of Foreign Affairs, and wife Minu Barati
- Rajiv Gandhi, Indian politician, and wife Sonia Gandhi, politician
- Phil Gramm, United States Senator, and wife Wendy Lee
- Jack Layton, Canadian NDP Leader, and wife Olivia Chow
- Chai Ling, Tiananmen protestor, and husband Robert A. Maginn Jr.
- Sir Seretse Khama, first President of Botswana, and his wife Ruth (née Williams).
- Clarence Thomas, Supreme Court Justice and his wife, Virginia
- David Wu, United States Congressman (D-OR), and wife Michelle.
- Marian Wright Edelman founder, Children's Defense Fund, and her husband Peter (since 1968)
Law
Literature
- Isabel Allende, writer, and her husband Willie Gordon
- Amiri Baraka (aka Leroi Jones), poet and his wife Hettie Jones writer (married 1960-1965)
- Iris Chang, writer, and husband Brett Douglas
- Leslie Charteris(Leslie Charles Bowyer Yin), writer, and wives Pauline Schishkin, Barbara Meyer, Elizabeth Bryant Borst, Audrey Long
- Alexandre Dumas, fils, novelist and (1) his wife Nadeja Naryschkine (deceased) (2) his wife Henriette Régnier
- Alexandre Dumas, père (Dumas Davy de la Pailleterie), novelist and (1) his wife Ida Ferrier, actress (2) his mistress, Marie-Catherine Labay, dressmaker
- Le Ly Hayslip, author, and husband
- Gish Jen and husband David O'Connor
- Maxine Hong Kingston, writer and husband Earll Kingston
- Evelyn Lau, poet, novelist, and W. P. Kinsella, novelist
- C.Y. Lee, writer, and late wife Joyce
- Bette Bao Lord, writer, and husband Winston Lord
- Walter Mosley, writer, and his wife Joy Kellman, dancer and choreographer
- Aleksandr Sergeyevich Pushkin, author, and his wife Natalya Goncharova
- George Schuyler, author and journalist, and his wife Josephine Cogdell, artist
- Amy Tan, writer, and husband Lou De-Mattei
- Alice Walker, novelist, and her former husband Mel Leventhal
- Michelle Sagara West, writer, and husband
- Lois-Ann Yamanaka, author, and husband John Inferrera
- Zhai Zhenhua, writer, and husband Charles B. Daniels
Media
- Emanuel Ax, pianist, and wife Yoko Nazaki
- Julie Chen, newscaster, and husband Les Moonves
- Connie Chung, newscaster and husband Maury Povich, TV personality
- Roger Ebert, film critic and author, and his wife Chaz Hammersmith
- Michelle Malkin, journalist, and her husband
- Rupert Murdoch, media proprietor, and wife Wendi Deng
- Shadoe Stevens, TV & Radio presenter and his wife
- Miyuki Tanobe, painter, and husband Maurice Savignac
- Montel Williams, TV personality and his wife
Military
Science
Sports
- Boris Becker, tennis player, and his wife Barbara
- Barry Bonds, baseball player, and his wife Liz
- Kobe Bryant, professional basketball player, and his wife Vanessa Laine
- Bruce Lee, martial artist and actor, and his wife Linda
- Debi Thomas, skater, and her husband
- Tiger Woods, golfer, and his wife Elin Nordegren
- Kristi Yamaguchi, skater, and husband Bret Hedican, hockey player
- Christian Karembeu, football player , and his wife Adriana Sklenarikova, model
Royalty
Other Notable Personalities
- Leroy Chiao, Astronaut, and wife Karen
- Oscar de la Renta, designer, and his wife Annette, socialite
- Diana, Princess of Wales and (1) Dr. Hasnat Khan, (2) companion Dodi al-Fayed
- Gloria Rubio y Alatorre, (better known as Gloria Guinness), socialite and (1) husband Count Franz Egon von Fürstenberg-Herdringen, aristocrat (2) husband Ahmed Fakhri, aristocrat and (3) Group Capt. Thomas Loel Guinness, Member of Parliament and Guinness heir
- Vera Wang, fashion designer, and husband Arthur Becker
Historical
- Alexander the Great and his wife Roxana of Persia
- Fletcher Christian, sailor and mutineer, and his Tahitiand wife Maimiti
- Marquis Antoine-Alexandre Davy de la Pailleterie, France’s Commissaire Général in the Artillery in the colony of Santo Domingo (Haiti), and his wife Marie-Céssette Dumas, a slave
- General Thomas-Alexandre Dumas (Thomas-Alexandre de la Pailleterie) and his wife Marie-Louise Elizabeth Labouret
- Ibrahim Abram Petrovich Gannibal, abducted Abyssinian noble, later courtier to Peter the Great, and (1) his wife (?) (divorced), (2) his wife Christina-Regina Scherberg
- Thomas Jefferson and Sally Hemings, his slave (hotly debated)
- John Rolfe, English colonist of Virginia, and his wife Pocahontas
- Sacajawea the Shoshone Indian guide with the Lewis and Clark Expedition and French-Canadian explorer Toussaint Charbonneau
Fictional
Notorious inter-ethnic couples
