Georgia ratified the Constitution on January 2, 1788. Its Senate seats were declared vacant in March 1861 owing to its purported secession from the Union. They were again filled from February 1871.
Class 2
| Senator | Party | From
| To |
| William Few | Anti-Administration | March 4, 1789 | March 3, 1793 |
| James Jackson | Anti-Administration | March 4, 1793 | 1795 |
| George Walton | Federalist | November 16, 1795 | February 20, 1796 |
| Josiah Tattnall | Republican | February 20, 1796 | March 3, 1799 |
| Abraham Baldwin | Republican | March 4, 1799 | March 4, 1807 |
| George Jones | Democrat | August 27, 1807 | November 7, 1807 |
| William H. Crawford | Republican | November 7, 1807 | March 23, 1813 |
| William B. Bulloch | Republican | April 8, 1813 | November 6, 1813 |
| William W. Bibb | Republican | November 6, 1813 | November 9, 1816 |
| George M. Troup | Republican | November 13, 1816 | September 23, 1818 |
| John Forsyth | Republican | November 23, 1818 | February 17, 1819 |
| Freeman Walker | Republican | November 6, 1819 | August 6, 1821 |
| Nicholas Ware | Republican | November 10, 1821 | September 7, 1824 |
| Thomas W. Cobb | Republican | December 6, 1824 | 1828 |
| Oliver H. Prince | Republican | November 7 1828 | March 3, 1829 |
| George M. Troup | Democrat | March 4, 1829 | November 8, 1833 |
| John P. King | Democrat | November 21, 1833 | November 1, 1837 |
| Wilson Lumpkin | Democrat | November 22, 1837 | March 3, 1841 |
| John M. Berrien | Whig | March 4, 1841 | May 1845 |
| John M. Berrien | Whig | November 13, 1845 | May 28, 1852 |
| Robert M. Charlton | Democrat | May 31, 1852 | March 3, 1853 |
| Robert A. Toombs | Whig,
Democrat | March 4, 1853 | February 4, 1861 |
| Homer V. M. Miller | Democrat | February 24, 1871 | March 3, 1871 |
| Thomas M. Norwood | Democrat | November 14, 1871 | March 3, 1877 |
| Benjamin H. Hill | Democrat | March 4, 1877 | August 16, 1882 |
| Middleton P. Barrow | Democrat | November 15, 1882 | March 3, 1883 |
| Alfred H. Colquitt | Democrat | March 4, 1883 | March 26, 1894 |
| Patrick Walsh | Democrat | April 2, 1894 | March 3, 1895 |
| Augustus O. Bacon | Democrat | March 4, 1895 | February 14, 1914 |
| William S. West | Democrat | March 2, 1914 | November 3, 1914 |
| Thomas W. Hardwick | Democrat | November 3, 1914 | March 3, 1919 |
| William J. Harris | Democrat | March 4, 1919 | April 18, 1932 |
| John S. Cohen | Democrat | April 25, 1932 | January 11, 1933 |
| Richard B. Russell, Jr. | Democrat | January 12, 1933 | January 21, 1971 |
| David H. Gambrell | Democrat | February 1, 1971 | November 7, 1972 |
| Samuel A. Nunn | Democrat | November 8, 1972 | January 3, 1997 |
| Max Cleland | Democrat | January 3, 1997 | January 3, 2003 |
| Saxby Chambliss | Republican | January 3, 2003 | present |
Class 3
| Senator | Party | From
| To |
| James Gunn | Democrat,
Federalist | March 4, 1789 | March 3, 1801 |
| James Jackson | Republican | March 4, 1801 | March 19, 1806 |
| John Milledge | Republican | June 19, 1806 | November 14, 1809 |
| Charles Tait | Republican | November 27, 1809 | March 3, 1819 |
| John Elliott | Republican | March 4, 1819 | March 3, 1825 |
| John M. Berrien | Republican | March 4, 1825 | March 9, 1829 |
| John Forsyth | Democrat | November 9, 1829 | June 27, 1834 |
| Alfred Cuthbert | Democrat | January 12, 1835 | March 3, 1843 |
| Walter T. Colquitt | Democrat | March 4, 1843 | February 1848 |
| Herschel V. Johnson | Democrat | February 4, 1848 | March 3, 1849 |
| William C. Dawson | Whig | March 4, 1849 | March 3, 1855 |
| Alfred Iverson | Democrat | March 4, 1855 | January 28, 1861 |
| Joshua Hill | Republican | February 1, 1871 | March 3, 1873 |
| John B. Gordon | Democrat | March 4, 1873 | May 26, 1880 |
| Joseph E. Brown | Democrat | May 26, 1880 | March 3, 1891 |
| John B. Gordon | Democrat | March 4, 1891 | March 3, 1897/td> |
| Alexander S. Clay | Democrat | March 4, 1897 | November 13, 1910 |
| Joseph M. Terrell | Democrat | November 17, 1910 | July 14, 1911 |
| Hoke Smith | Democrat | November 16, 1911 | March 3, 1921 |
| Thomas E. Watson | Democrat | March 4, 1921 | September 26, 1922 |
| Rebecca L. Felton | Democrat | November 21, 1922 | November 22, 1922 |
| Walter F. George | Democrat | November 22, 1922 | January 2, 1957 |
| Herman E. Talmadge | Democrat | January 3, 1957 | January 3, 1981 |
| Mack Mattingly | Republican | January 3, 1981 | January 3, 1987 |
| Wyche Fowler | Democrat | January 3, 1987 | January 3, 1993 |
| Paul Coverdell | Republican | January 3, 1993 | July 18, 2000 |
| Zell Miller | Democrat | July 27, 2000 | January 3, 2005 |
| Johnny Isakson | Republican | January 3, 2005 | present |
