Isomerase
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In biochemistry, an isomerase is any enzyme that catalyses the interconversion of isomers. Isomerases thus catalyze reactions of the form
- A → B
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Nomenclature
The names of isomerases are formed as "substrate isomerase" (for example, enoyl CoA isomerase), or as "substrate type of isomerase" (for example, phosphoglucomutase).
Classification
Isomerases are classified as EC 5 in the EC number classification of enzymes. Isomerases can be further classified into six subclasses:
- EC 5.1 includes enzymes that catalyze racemization (racemases) and epimerization (epimerases)
- EC 5.2 includes enzymes that catalyze the isomerization of geometric isomers (cis-trans isomerases)
- EC 5.3 includes intramolecular oxidoreductases
- EC 5.4 includes intramolecular transferases (mutases)
- EC 5.5 includes intramolecular lyases
- EC 5.99 includes other isomerases
See also
References
EC 5 Introduction (http://www.chem.qmul.ac.uk/iubmb/enzyme/EC5/intro.html) from the Department of Chemistry at Queen Mary University of Londonfr:Isomérase