1519
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| Years: 1516 1517 1518 - 1519 - 1520 1521 1522 | |
| Decades: 1480s 1490s 1500s - 1510s - 1520s 1530s 1540s | |
| Centuries: 15th century - 16th century - 17th century | |
Events
- March 4 - Hernán Cortés lands in Mexico.
- June 28 - Charles I of Spain becomes Emperor of Holy Roman Empire as Charles V, Holy Roman Emperor (ruled until 1556).
- September 20 - Ferdinand Magellan leaves Europe to circumnavigate the world.
- November 8 - Hernán Cortés enters Tenochtitlán and Aztec ruler Moctezuma welcomes him with great pomp as would befit a returning god.
- Erasmus publishes his Colloquia.
- Martin Luther questions the infallibility of papal decrees.
- Mannerism, artistic form appears in Italy and spreads.
- Spanish find Barbados.
- Cacao comes to Europe.
- Panama founded.
Births
- February 16 - Gaspard de Coligny, French Huguenot leader (died 1572)
- February 17 - Francis, Duke of Guise, French soldier and politician
- March 31 - Henry II of France, member of the Valois Dynasty (died 1559)
- April 13 - Catherine de Medici, Queen of France (died 1589)
- May 27 - Girolamo Mei, Italian historian and humanist (died 1594)
- June 6 - Andrea Cesalpino, Italian physician (died 1603)
- June 12 - Cosimo I de' Medici, Grand Duke of Tuscany (died 1575)
- June 15 - Henry Fitzroy, 1st Duke of Richmond and Somerset, illegitimate son of Henry VIII of England (died 1536)
- June 24 - Theodore Beza, French theologian (died 1605)
- July 22 - Pope Innocent IX (died 1591)
- Thoinot Arbeau, French priest and author (died 1596)
- Catherine de Bourbon, wife of Henry I, Duke of Lorraine (died 1604)
- René of Châlon, Prince of the House of Orange (died 1544)
- Thomas Gresham, English merchant and financier (died 1579)
- Nicholas Grimald, English poet (died 1562)
- Catherine de' Medici, queen of France
- Pedro Menéndez de Avilés, first Spanish governor of Florida
- Ikeda Nagamasa, kokujin and military commander (died 1563)
- Edwin Sandys, English prelate (died 1588)
- Imagawa Yoshimoto, Japanese daimyo
- Stanislaw Zamoyski, Polish nobleman (died 1572)
Deaths
- January 12 - Maximilian I, Holy Roman Emperor (born 1459)
- January 21 - Vasco Núñez de Balboa, Spanish explorer (born 1475)
- May 2 - Leonardo da Vinci, Italian inventor and painter (born 1452)
- June 24 - Lucrezia Borgia, illegitimate daughter of Pope Alexander VI (born 1480)
- August 11 - Johann Tetzel, German Dominican priest (born 1465)
- September 10 - John Colet, English churchman and educational pioneer (born 1467)
- Francesco II of Gonzaga, Marquis of Mantua (born 1466)
- William Grocyn, English scholar (born 1446)
- Ambrosius Holbein, German painter (born 1494)
- Lorenzo II de' Medici, Duke of Urbino (born 1492)
- Alonso Alvarez de Pineda, Spanish explorer and cartographer (born 1494)af:1519
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