William Parsons
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- William Parsons, 3rd Earl of Rosse, usually known as Lord Rosse, was a 19th-century Irish astronomer.
- William Parsons (musician) (1786 - 1817) was Master of the King's Music.
- William Barclay Parsons (1859 - 1932) was a famous American civil engineer.
- Rear Admiral William Sterling "Deak" Parsons, weaponeer on the Enola Gay (at the time, had rank of Captain).
- William W. Parsons, named manager of NASA's space shuttle program in 2003.
- William Parsons (1701-1757), Surveyor General and Founder of Easton, Pennsylvania.
- William Parsons (scientist) is a physicist at the University of Maryland, College Park.