William Mayo
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William Mayo is the name of:
- A former chief engineer of the Ford Motor Company, William B. Mayo.
- Two co-founders of the Mayo Clinic, William Worrall Mayo and William James Mayo.
- The civil engineer, born in about 1685, who laid out the city of Richmond, Virginia.
- The vicar of Folke, Dorset, England in about 1845.
- The founder and first president of East Texas Normal College, William Leonidas Mayo.