Signal-recognition particle
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A signal-recognition particle or SRP is a cytosolic particle that transiently binds:
- To the endoplasmic reticulum (ER) signal sequence in a nascent protein
- To the large ribosomal unit
- To the SRP receptor
SRP and its receptor initiate the transfer of the nascent chain across the ER membrane. Once the chain reaches the translocon, SRP and its receptor dislocate.
Components
- P54
- P9
- P14
- P68
- P72