Small interfering RNA
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Small interfering RNA (siRNA) are a class of 20-25 nucleotide-long RNA molecules that interfere with the expression of genes. These are produced as part of the RNA interference (RNAi) process by the enzyme Dicer.
External links
- First description of siRNA's (1999). (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10542148&query_hl=3)
- siDirect: a web-based online software system for computing siRNA sequences (http://design.rnai.jp/)
- Paper describing siDirect (http://nar.oupjournals.org/cgi/content/full/32/suppl_2/W124)
- Paper describing effectivity of siDirect (http://nar.oupjournals.org/cgi/content/full/32/3/936)
- HuSiDa: Human siRNA Database (http://www.human-siRNA-database.net)
- siRNAdb: a database of siRNA sequences (http://siRNA.cgb.ki.se)