SeT interrupts
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In x86 assembly, STI is a mnemonic for SeT Interrupts. It sets the IF flag to one, so external interrupts are serviced. An opcode with opposite functionality is CLI, which sets IF = 0 and tells the CPU not to service external interrupts.
Any software interrupts will be serviced whether IF = 1 or 0. A software interrupt is one called by the instruction INT xx.