Charcot's triad

There are two sets of Charcot's triads, both of which are sets of clinical signs relating to quite separate diseases. One pertains to multiple sclerosis while the other refers to cholangitis. Charcot's triads are named after Jean-Martin Charcot (1825-1893), the French neurologist who first described these combinations of signs in relation to these diseases.

For multiple sclerosis - Charcot's triad consists of dysarthria, ataxia and tremor.

For cholangitis - Charcot's triad consists of abdominal pain in the right upper quadrant, fever and jaundice. Charcot's triad combined with hypotension and altered mentation (stupor/coma or confusion) is called Reynolds' pentad.

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