Buspirone
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Buspirone.png
chemical structure of buspirone
Buspirone (Ansial®; Ansiced®; Anxiron®; Axoren®; Bespar®; Buspar®; Buspimen®; Buspinol®; Buspisal®; Narol®) is an anxiolytic drug. It generally is considered to have a significantly lower addiction potential compared to other drugs commonly prescribed for anxiety, especially benzodiazepine medications. Furthermore, it is non-sedating. It is thought to act by interfering with the function of the neurotransmitter serotonin in the brain, particularly by serving as a 5-HT1A receptor partial agonist. Bristol-Myers Squibb gained FDA approval for Buspirone in 1986. The drug went generic in 2001.
No effect on GABA-receptors; partial agonist at 5-HT1A receptors.
Buspirone should be taken in moderation; an increase in blood pressure is among the side effects the medicine can have.
Template:Treatment-stub It is also useful as an augmenting agent, for the treatment of depression, when added to SSRI's (selective serotonin reuptake inhibitors)