Talk:Epinephrine

From Academic Kids

Adrenaline is, to my knowledge, NOT a tradename but rather another form of the chemical name (in fact it´s just the same as epinephrine, only in Latin instead of Greek). Kosebamse 14:16 Mar 7, 2003 (UTC)

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How shocking! You scientists are renaming Adrenaline? I've never heard of Epinephrine. How do you pronounce it? (maybe someone should add that)

I can't really imagine all of us extreme sports people going

   "Woah! That was awesome. What an ephinephrine rush!"

Nojer2 16:46 Mar 7, 2003 (UTC)

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I remove the following phrase:

but this trend seems to be coming to an end as the international community (especially Europe) pushes towards using non-propriety naming conventions (Adrenaline has been used a trade name).

It's correct that "Europe" (in this case rather West-Europe) pushes for non-propriety names, but that is no reason for the wordings about "this trend" "coming to an end".

-- Johan Magnus 03:26 19 May 2003 (UTC)

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I´ve rewritten much of the article, and, among others, removed this:

In Europe "epinephrine" is perceived as an Americanization of the British-approved name, "adrenaline."

I don´t think this helps understand what adrenaline/epinephrine is and does.

to lower intra-ocular pressure in the treatment of glaucoma and to treat acute chloroquine poisoning.

I wonder whether epinephrine can really lower intraocular pressure (dilating the pupils generally doesn´t help to that purpose); and the chloroquine reference is not too interesting in a general encyclopedic article. Some more stuff that I´ve left out would, I think, really belong to an article stress reaction or sympathetic nervous system. Unfortunately, the latter is currently just a redirect to Autonomic nervous system and that article itself needs much work to become more readable and useful. Kosebamse 13:55 19 May 2003 (UTC)

Very good!
Also the polemics has been removed step by step, as it looks from the history.
Maybe it would be of some interest, though, to keep some kind of reference to US-usage versus British/European usage. There aren't supposed to be synonyms in English on such basic things, are there? ;-) (It's another thing that the French can't use American terms all the time, that is selfevident, all the world understand that, but the English... ;-)))
-- Ruhrjung 21:15 20 May 2003 (UTC)

Of course it might be of interest to know how and why American and British English differ in this respect, but those questions do not, IMO, belong into an article about a hormone/drug. It should be noted that many drugs (at least in the EU) are sold under generic names (sometimes slightly modified) rather than trade names. Therefore, it would be not that unusual to see epinephrine/adrenaline being sold as "Adrenaline" or "Adrenaline-Foobar". Kosebamse 06:29 21 May 2003 (UTC)

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Allergy patients undergoing immunotherapy can get an epinephrine rinse before their allergan extract is administered.
I wonder where this comes from and what it is supposed to mean. Epinephrine does not act as a specific antagonist in anaphylaxis, rather it is used as a symptomatic treatment against anaphylactic symptoms. Furthermore, the extreme and possibly lethal side effects of epinephrine make it highly unlikely that it could be used for such prophylactic purposes. Kosebamse 20:48 31 May 2003 (UTC)

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to Kosebamse, [[adrenaline]] is not a trade mark, but [[Adrenalin]] is

Adrenaline vs. Epinephrine

There are various national bodies for standardizing the nonproprietary names for drugs. In the UK, they use British Approved Names (BAN), in the U.S. they use U.S. Approved Names (USAN) etc... The World Health Organization designates International Nonproprietary Names. In most cases, all these groups agree, this is an exception. Although I haven't been able to find a full list of INNs, this document[1] (http://medicines.mhra.gov.uk/inforesources/productinfo/banadrnor_apr04.pdf) reliably indicates that epinephrine is the INN for adrenaline (which is BAN). I think we should go with INNs for all applicable cases (with redirects of course). Matt 04:25, 26 Jun 2004 (UTC)

Use in anaesthesiology?

It seems like more could be said about the physiological effects of epinephrine, but I was reading various issues of an anaesthesiology journal once and much mention was made of epinephrine as a resuscitative and/or post-operative aid. Also, if I recall correctly, the concentrations of epinephrine involved were very small, so maybe a note on its power (signal cascading?) could also be added. I'd put this stuff in myself but it's not my field. I'll try to look it up again if no one else responds though. Jeeves 15:53, 15 Apr 2005 (UTC)