Talk:Clostridium difficile

I just found this site while looking for information on clostridium difficile. I have been suffering with recurrent c-diff since September 2003. I have had three relapses. I was first put on Flagyl for 10 days. The c-diff recurred after off Flagyl four days. Next put on Vancocin 250 mg/four a day for 14 days. Four days off the Vancocin it came back. Next tried a pulse-dosing of Vancocin. When I got down to one every four days it came back. I took full dosage again and have tapered down to one every three days. I am symptom free at that dose. I am afraid to go longer that one every three days. But will at some point...don't want to be on this medicine forever.... The way I came down with c-diff : I have a mitral valve prolapse so took 3000 mg/amoxicillin in one day for teeth cleaning. One week later took Cipro 500mg three times a day for 10 days for UTI. Five days later had worse form of c-diff colitis. Psuedomembraneous Colitis. I am hoping to rid myself of this horrible bacteria soon. I had never heard of this before I came down with it. I am now an advocate for no antibiotics. And the overuse and abuse of them by physicians. If this helps one person think twice before blindly taking an antibiotic it will have been worth my time...

C Dif is a nightmare!

My son is 2 1/2 years old and he has C Dif...he had an ear infection a few months back and was given antibiotics...then a second dose of a different antibiotic when the ear infection was still there. A side effect of the antibiotic was loose stool, but when it continued long after he finished the antibiotic, he had his stool tested and was positive for C Dif. He was put on the Flagyl as well, which hasn't done a thing. It was also the nastiest medicine to have to give a child. The pharmacist tried to flavor it, but it leaves the worst after taste. I made the mistake of giving it to him after a meal, which was promptly vomited up...I'm waiting for the results of his second stool sample, and I'm sure that he still has it. This is a very difficult thing to deal with when it's a child- I will most certainly be questioning the necessity of any antibiotics he may need in the future...

INFORMATION ON THE CURE FOR C-DIFF DISEASE FROM - I ALWAYS WIN

VANCOCYN IS THE MINIMUM. FLAGYL IS FOR THIRD WORLD COUNTRIES THAT DO NOT HAVE HEALTH CARE. FLAGYL IS A TEMPORARY REMEDY THAT FAILS %90 of the time. VANCOCYN IS THE MINIMUM. VANCOCYN WILL SAVE YOUR LIFE BUT IT WILL NOT SAVE YOUR INSIDES FROM TRAUMA. THE INSTESTINE IS NOW PRONE TO MASSIVE INFECTIONS AND EXTREMLY SENSITIVE TO ANY AND ALL INFECTIONS. THE INTESTINES NO LONGER FUNCTION WITH NORMAL HUMAN IMMUNITY AND NEVER WILL UNLESS; "Z" ANTIOBIOTIC is administered via pick line fore a minimum of three consecutive days. FOLLOWED WITH A MINIMUM OF 160mg of Potassium and NORMAL SALINE TITRATED AT 1000 ML per 8 to twelve hours. THE NORMAL SALINE AND "Z" antibiotic are mandatory. The two used together cause a variable. The variable is THE NORMAL SALINE MAY DILUTE ANTIBIOTIC "Z" thus to formulate a positive outcome with this variable, increase the amount of days of antibiotic "Z" via pick line to SIX DAYS MINIMUM.

ALL FOOD IN THE WORLD CONTAINS BACTERIA, THUS A C-DIFF PATIENT IS NOW MASSIVLY PRONE TO INFECTION WITH IN THE ENTIRE INTESITINE. THESE INFECTIONS COUSE THE FLARE UPS. ORAL ANTIBIOTICS ARE FAILURE AND OLNY A SHORT TERM REMEDY. "Z" antibiotic via pic line is the cure to end the misery of this war.

COUTION; MILK is a RED FLAG and or a BLACK FLAG for the rest of your natural born life. TO FIND POTASSIUM, EAT ONE HEALTHY BANNANA FOR THE REST OF YOUR NATURAL LIFE.

I AM QUALITY OF LIFE ISSUE # 1 ; QUALITY OF LIFE INDEX: CANCER - QUALITY BEFORE COST MR. CEO This is based on adult dosages. ALL PEDIATRIC MEDICAL PRACTICES ARE "EXPERIMENTAL" in the world. This is a medical secret. YES the same medications the same routes for peditrics have proven success. "Z" antibiotic is a "COMBINATION ANTIBIOTIC".

YOUR TRULY,

FRONT LINE AMERICAN SUPERMAN PARAMEDIC LARRY --Larrygray 07:10, 9 May 2005 (UTC)

Odd sentence.

Hi, I know pretty much nothing about this organism. :) So, I don't know if this sentence near the bottom of the article is correct, incorrect, or just poorly worded.

"Two antibiotics are effective against C. difficile. Metronidazole is first choice because of superior tolerability, lower price and comparable efficacy."

This sentence implies that Metronidazole has both a lower price and comparible efficiancy, but this sounds odd as it's supposed to be the first choice when fighting this thing. If it does indeed have a lower efficiancy, that's fine, but if it has a superior one, then I think the sentence should be rephrased as "...superior tolerability, comparable efficacy and lower price." If someone could clarify this, that would be great. --Sparky the Seventh Chaos 05:23, May 22, 2005 (UTC)

Fact is - Metronidazole is a failure in more than %90 of the time. Metronidazole may work in a chem lab dish but it does not effectivley cure this disease.

Larry Gray