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SRY

From Academic Kids

SRY is the sex-determining Y chromosome gene in humans and other primates, linked to determining males. It is not the only, or even most common sex-determining gene in mammals. Most non-primate mammals use the Y chromosome gene UBE1 for the same purpose.

Here are proofs that SRY indeed determines maleness.

  • Humans with Y chromosome and many X chromosomes (XXY, XXXY etc.) are males.
  • There are males of XX karyotype. It turns out that these males have SRY gene in one or both X chromosomes. (However, these males are infertile.)
  • Similarly, there are females of XXY karyotpe. These females have no SRY gene in their Y chromosome.
  • Using genetical engineering, mice with XX karyotype but with SRY gene in one of their X chromosomes were made. These mice appeared to be male.

On Olympic games, athletes with SRY gene are not permitted to participate as females.


Other meanings

SRY is a TLA that could mean:

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