Hot 100 No. 1 Hits of 2001 (USA)
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These are the #1 Hits of 2001:
| Issue Date | Song Title | Artist |
| January 6 | Independent Women | Destiny's Child |
| January 13 | Independent Women | Destiny's Child |
| January 20 | Independent Women | Destiny's Child |
| January 27 | Independent Women | Destiny's Child |
| February 3 | It Wasn't Me | Shaggy featuring Ricardo "RikRok" Ducent |
| February 10 | It Wasn't Me | Shaggy featuring Ricardo "RikRok" Ducent |
| February 17 | Ms. Jackson | OutKast |
| February 24 | Stutter | Joe featuring Mystikal |
| March 3 | Stutter | Joe featuring Mystikal |
| March 10 | Stutter | Joe featuring Mystikal |
| March 17 | Stutter | Joe featuring Mystikal |
| March 24 | Butterfly | Crazy Town |
| March 31 | Angel | Shaggy featuring Rayvon |
| April 7 | Butterfly | Crazy Town |
| April 14 | All For You | Janet |
| April 21 | All For You | Janet |
| April 28 | All For You | Janet |
| May 5 | All For You | Janet |
| May 12 | All For You | Janet |
| May 19 | All For You | Janet |
| May 26 | All For You | Janet |
| June 2 | Lady Marmalade | Christina Aguilera/Pink/Lil' Kim/Mya |
| June 9 | Lady Marmalade | Christina Aguilera/Pink/Lil' Kim/Mya |
| June 16 | Lady Marmalade | Christina Aguilera/Pink/Lil' Kim/Mya |
| June 23 | Lady Marmalade | Christina Aguilera/Pink/Lil' Kim/Mya |
| June 30 | Lady Marmalade | Christina Aguilera/Pink/Lil' Kim/Mya |
| July 7 | U Remind Me | Usher |
| July 14 | U Remind Me | Usher |
| July 21 | U Remind Me | Usher |
| July 28 | U Remind Me | Usher |
| August 4 | Bootylicious | Destiny's Child |
| August 11 | Bootylicious | Destiny's Child |
| August 18 | Fallin' | Alicia Keys |
| August 25 | Fallin' | Alicia Keys |
| September 1 | Fallin' | Alicia Keys |
| September 8 | I'm Real | Jennifer Lopez featuring Ja Rule |
| September 15 | I'm Real | Jennifer Lopez featuring Ja Rule |
| September 22 | I'm Real | Jennifer Lopez featuring Ja Rule |
| September 29 | Fallin' | Alicia Keys |
| October 6 | Fallin' | Alicia Keys |
| October 13 | Fallin' | Alicia Keys |
| October 20 | I'm Real | Jennifer Lopez featuring Ja Rule |
| October 27 | I'm Real | Jennifer Lopez featuring Ja Rule |
| November 3 | Family Affair | Mary J. Blige |
| November 10 | Family Affair | Mary J. Blige |
| November 17 | Family Affair | Mary J. Blige |
| November 24 | Family Affair | Mary J. Blige |
| December 1 | Family Affair | Mary J. Blige |
| December 8 | Family Affair | Mary J. Blige |
| December 15 | U Got It Bad | Usher |
| December 22 | How You Remind Me | Nickelback |
| December 29 | How You Remind Me | Nickelback |
Artists at No. 1 for first time this year
- Shaggy - It Wasn't Me
- Outkast - Ms. Jackson
- Joe and Mystikal - Stutter
- Crazy Town - Butterfly
- Pink, Mya, and Lil' Kim - Lady Marmalade
- Alicia Keys - Fallin'
- Mary J. Blige - Family Affair
- Nickelback - How You Remind Me
2001 was a rather notable year in the Hot 100, because we saw artists that had been out since the early and mid-90's hit No. 1 for the first time this year. Lil' Kim became the first female rap artist to hit No. 1 on the Hot 100.
See also: List of Number 1 Hits (USA) Template:Top 100