Adenosine triphosphate

In biochemistry, adenosine triphosphate (ATP) is nucleotide, known as the "molecular currency" of intracellular energy transfers. ATP is a means of storing and transporting chemical energy; both within the cells, and as a precursor for the formation of nucleic acids. Chemically, ATP consists of adenosine and three phosphate groups; energy is released, by hydrolysis of the third phosphate group. Having released the phosphate group, ATP can absorb energy and regain the group; this allows ATP to store energy, like a "battery".

Production

ATP can be produced by various cellular processes, most typically by oxidative phosphorylation in mitochondria or photosynthesis in chloroplasts.

Other triphosphates

Living cells also have other "high-energy" nucleoside triphosphates, such as guanine triphosphate. Between them and ATP, energy can be easily transferred with reactions such as those catalyzed by nucleoside diphosphokinase: Energy is released when hydrolysis of the phosphate-phosphate bonds is carried out. This energy can be used by a
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variety of enzymes, motor proteins, and transport proteins to carry out the work of the cell. Also, the hydrolysis yields free inorganic phosphate and adenosine diphosphate, which can be broken down further to another phosphate ion and adenosine monophosphate. ATP can also be broken down to adenosine monophosphate directly, with the formation of pyrophosphate. This last reaction has the advantage of being effectively irreversible in aqueous solution.

Reaction of ADP with GTP

ADP + GTP ATP + GDP

There is talk of using ATP as a power source for nanotechnology and implants. Artificial pacemakers could become independent of batteries.

See also

cyclic adenosine monophosphate, adenosine monophosphate, adenosine diphosphate, and phosphagens